Abstract Age-related macular degeneration (AMD) is a leading cause of irreversible central vision loss in older adults and evolves along a continuum from early and intermediate non-exudative (“dry...
An AMD Patient’s Journey: Education, Self‑Management, and Rehabilitation
Abstract Age-related macular degeneration (AMD) is a leading cause of irreversible central vision loss and affects millions of older adults worldwide, including an estimated 2.5 million Canadians.(...
Digital Companions and Health Coaching for Older Adults with Chronic Eye Disease
Abstract Digital health technologies (DHTs)—including mobile apps, web platforms, and intelligent voice assistants—are increasingly used to support self-management and adherence in chronic disease,...
Adherence to Oral Eye Supplements: General Principles and Practical Strategies
Abstract Adherence to oral therapies, including eye-targeted nutritional supplements, is a pervasive challenge in chronic disease management, with typical adherence rates for long-term medications ...
Patients, AREDS2 Supplements, and Real‑World Adherence
Abstract AREDS and AREDS2 established that high-dose antioxidant vitamins, zinc, copper, lutein, and zeaxanthin reduce progression to advanced age-related macular degeneration (AMD) in patients wit...
Mitochondrial Dysfunction in Retinal Aging and Age-Related Macular Degeneration
Abstract Mitochondria are essential for retinal cell survival, providing ATP for phototransduction and ion homeostasis while regulating redox balance, calcium signalling, and apoptosis.(1,2) The ne...